Anti-mildew agent manufacturers explain to you how to prevent mildew!
Anti-mildew agent manufacturers of anti-mildew agent refers to an additive to prevent mold breeding. Food, fruit, feed, cosmetics, coatings, adhesives, leather, aquatic products, plastics, etc., are prone to mold contamination during use and storage, making the finished products deteriorate. In order to prevent the growth of mold, it is necessary to add anti-mold agents to the product.
Affect metabolism
1, inhibit enzyme activity:
(1) chelate with the activator of the enzyme (metal ions) to inhibit the activity of the enzyme: the anti-mold substance can interfere with the use of metals in the cell, thus inhibiting the activity of the enzyme, binding the metal in a certain space, so that microorganisms can not use it; It can also enter microbial cells and bind metals inside them.
(2) Destroy the three-dimensional configuration of the enzyme, denaturating and inactivating the enzyme: When the anti-mildew substance destroys the spatial configuration of the enzyme protein, it will inevitably break up its active center and make the enzyme lose its vitality;
③ Inhibit enzyme activity: the anti-mold agent can interact with the active groups of amino acid residues in the activity center of the enzyme -SH, -OH, etc., so that the chemical properties of these active groups change, and the spatial configuration does not change, but the enzyme activity decreases or even loses;
2, inhibit respiration: anti-mildew substances can inhibit the dehydrogenation of the matrix, can inhibit some enzymes related to respiration, can inhibit electron transfer and so on.
Second, damage the cell structure
1, damage to the cell wall: antibacterial substances can competitively inhibit the enzymatic reaction of synthetic cell wall components, thus inhibiting the synthesis of microbial cell walls. (Penicillin, cephalosporin, quaternary ammonium salt, lysozyme severing peptide glucan, aldehyde and amino reaction)
2. Damage the cell membrane: damage the connection between lipid molecules and proteins in the cell membrane, and damage the molecular structure of phospholipids; By changing the surface charge properties of the cell membrane, the permeability of the cell membrane is destroyed. Inhibit the synthesis of cell membrane by inhibiting the synthesis of various components of phospholipids.
3, damage the structure of the protein: antibacterial substances can denature and deactivate the enzyme, can interact with the sulfhydryl group and amino group of the protein, destroy the stereoconformation of the enzyme protein, and even decompose a part of the protein, so that the lipophilic bond between the protein chains is destroyed.
3. Damage nucleic acid structure, affecting microbial reproduction
1, mutation: anti-mildew agent can cause chromosome break and recombination; Some nucleotide base analogues are used to make the microbial cells mistakenly combine the synthetic DNA, replacing the normal nucleotide, resulting in chromosome aberration; The reaction with the amino or hydroxyl groups of DNA bases causes a change in the order of the bases during DNA replication, resulting in structural changes in the synthesized proteins and inactivation of enzymes.
2, inhibit chromosome division, affect mitosis:
① can react with the main material DNA in chromosomes, so that chromosomes can not be separated during mitosis;
Interferes with the formation of the spindle during mitosis, so that the daughter nuclear material cannot be pulled towards the new cell
